Intermediates for the preparation of condensed seven-membered ri

Details Intermediates for the preparation of condensed seven-membered ri Intermediates for the preparation of condensed seven-membered ri

1986-08-27

1988-04-19

Bond, Robert T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546245, 546248, C07D21144, C07D21194, C07D21186

Patent

active

047390662

ABSTRACT:
Novel condensed seven-membered ring compounds of the formula: ##STR1## [wherein R.sup.1 and R.sup.2 are independently hydrogen, halogen, trifluoromethyl, lower alkyl or lower alkoxy, or both jointly form tri- or tetramethylene; R.sup.3 and R.sup.5 are independently hydrogen, lower alkyl or aralkyl; R.sup.4 is hydrogen or lower alkyl; R.sup.6 is a condensed or non-condensed hetero-alicyclic containing at least one atom of N, O and S as a ring-forming atom which may be substituted; A is an alkylene chain; n is 1 or 2] and salts thereof.
These compounds exhibit inhibitory activity on angiotensin converting enzyme and so forth, and are of value as an agent for diagnosis, prevention and treatment of circulatory diseases, such as hypertension, cardiopathy and cerebral apoploxy.

REFERENCES:
patent: 4450248 (1984-05-01), Leistner et al.
patent: 4638800 (1987-01-01), Sugihara et al.

Affiliated with

Also associated with

Rating

Intermediates for the preparation of condensed seven-membered ri does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Intermediates for the preparation of condensed seven-membered ri, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Intermediates for the preparation of condensed seven-membered ri will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2176209