Thiazole derivatives

Details Thiazole derivatives Thiazole derivatives

1975-02-24

1976-09-07

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424270, C07D27722

Patent

active

039794024

ABSTRACT:
This invention relates to novel thiazole derivatives having the formula: ##SPC1##
Wherein R represents an unsubstituted or substituted aryl radical; R.sup.1 and R.sup.2 independently represent hydrogen or lower alkyl; R.sup.3 represents hydrogen or lower alkyl; and --COZ represents an amide group; a carboxylic acid group or an ammonium or pharmaceutically acceptable alkali metal or alkaline earth metal salt thereof; or an ester group of formula --COOR.sup.4 wherein R.sup.4 represents an alkyl, aralkyl or aryl radical, which exhibit antilipemic activity.

REFERENCES:
D. Jerassi et al., "J. of Organic Chem.," vol. XV, pp. 694-699 (1950).

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