Purification process for 7-aminocephalosporins

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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424246, C07D50112

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active

039793834

ABSTRACT:
Cephalosporin nucleus compounds represented by the formula: ##SPC1##
Wherein R is for example, acetoxy or a 1-(lower alkyl)-1H-tetrazole-5-yl, a 5-(lower alkyl)-1,3,4-thiadiazole-2-yl or a 5-(lower alkyl)-1,3,4-oxadiazole-2-yl group are purified via chromatography over the hydrophilic polyacrylic matrixed quaternary ammonium anionic exchange resin, Amberlite IRA-458.

REFERENCES:
patent: 3207755 (1965-09-01), Abraham et al.
patent: 3219662 (1965-11-01), Abraham et al.
patent: 3467654 (1969-09-01), McCormick

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