Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1980-09-17
1982-07-06
Sutto, Anton H.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
548262, 548333, 548336, 546193, 546210, 544366, C07D24908, C07D24106, C07D23310, C07D29502
Patent
active
043384536
ABSTRACT:
Novel aminoalkyl triazoles are provided which are useful for the treatment of sensitized humans and animals for allergies and anaphylactic reactions. Additionally, a number of the compounds are useful in the treatment of hypertension. These compounds are of the formula ##STR1## wherein R.sub.4 is hydrogen, alkyl, alkoxy, aryl, sulfonyl, or sulfinyl, R.sub.5 is aryl, R.sub.6 is hydrogen, hydroxy, alkyl, alkoxy, or alkanoyloxy, and R.sub.1 is piperidinyl or amino.
REFERENCES:
patent: 3505350 (1970-04-01), Doebel et al.
patent: 3651080 (1972-03-01), Doebel et al.
patent: 3882134 (1975-05-01), Baldwin et al.
patent: 3910943 (1975-10-01), Gall et al.
patent: 4102889 (1978-07-01), Baldwin et al.
patent: 4111944 (1978-09-01), Novello et al.
patent: 4115572 (1978-09-01), Paul et al.
patent: 4207324 (1980-06-01), Matsumura et al.
Agents and Actions, 9:235-238, (1979) H. G. Johnson, et al.
Journal of Medicinal Chemistry, 21, No. 6, 542-548, (1978), Martin Gall et al.
Merck Manual 12th ed. 465-471 (1972).
Goodman and Gillman: The Pharmacological Basis of Therapeutics, 4th ed., 728-744 (1970).
Antwoulers, F., et al., Experientia 33:1657 (1977).
Gonsior, E., et al., Intern. J. Clin. Pharmacol. and Biopharm. 17:283 (1979).
Gibson Sharon A.
Sutto Anton H.
The Upjohn Company
Welch Lawrence T.
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