Depyrogenation process

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Polymer from ethylenic monomers only

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210636, 422 28, 424 79, 424 85, 424 88, 424 89, 424177, 424180, 424181, 424183, 424341, 424343, 424361, 424366, A61K 3174, A61L 216

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active

044129858

ABSTRACT:
Products and materials used in the biomedical field are depyrogenated by prolonged contact with a solution or suspension of about 0.1% to about 10% by weight of a nonionic amphiphile selected from the group consisting of substances having the general formula RC.sub.6 H.sub.4 (OC.sub.2 H.sub.4).sub.n OH wherein R is octyl or nonyl and n is at least 3, followed by liquid phase separation of said amphiphile from the resulting depyrogenated product or material.

REFERENCES:
patent: 4020183 (1977-04-01), Asculai
patent: 4113712 (1978-09-01), Funakoshi
patent: 4118479 (1978-10-01), Prince et al.
patent: 4158054 (1979-06-01), Furminger et al.
Sweadner et al., Appl. & Environ. Microbiol., vol. 34, No. 4 (1977) pp. 382-386.
Sweadner--Chem. Abst. vol. 87 (1977) p. 206,453e.
Skelly et al., Nature, vol. 290, 51-54, Mar. 5, 1981.

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