Composition comprising a tramadol material and acetaminophen and

Details Composition comprising a tramadol material and acetaminophen and Composition comprising a tramadol material and acetaminophen and

1992-11-10

1994-08-09

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514646, A61K 31165

Patent

active

053366913

ABSTRACT:
This invention relates to a composition comprising a tramadol material and acetaminophen, and its use. As used herein tramadol refers to various forms of tramadol. The compositions are pharmacologically useful in treating pain and tussive conditions. The compositions are also subject to less opioid side-effects such as abuse liability, tolerance, constipation and respiratory depression. Furthermore, where the components of the compositions are within certain ratios the pharmacological effects of the compositions are superadditive (synergistic).

REFERENCES:
patent: 3652589 (1972-03-01), Flick et al.

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