Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H.su

Details Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H.su Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H.su

1986-09-25

1987-09-08

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544331, 544333, 546277, 546278, 548128, 548131, 548133, 548134, 548135, 548143, 548199, 548202, 548205, 548337, 548342, C07D27748

Patent

active

046925317

ABSTRACT:
Histamine H.sub.2 -receptor antagonists of the formula ##STR1## wherein A, m, Z, n and R.sup.1 are as defined herein, and their nontoxic pharmaceutically acceptable salts are novel anti-ulcer agents which are prepared by ring closure of a substituted ethanediimidamide of the formula ##STR2##

REFERENCES:
patent: 4374248 (1983-02-01), Crenshaw
patent: 4440933 (1984-04-01), Montzka

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