Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Skin cosmetic coating
Patent
1995-06-01
1997-06-17
Mosley, Terressa
Drug, bio-affecting and body treating compositions
Topical body preparation containing solid synthetic organic...
Skin cosmetic coating
424 59, 424 7802, 514844, 514846, 514847, 514937, 514938, A61K 742
Patent
active
056397976
DESCRIPTION:
BRIEF SUMMARY
The present invention relates to stable cosmetic compositions, in particular water-in-oil emulsions (W/O emulsions), which are protected against physical decomposition.
Skincare in the context of the invention is primarily to be understood as meaning intensifying, assisting and, if necessary, re-establishing the natural function of the skin as a barrier against environmental influences (for example dirt, foreign substances and microorganisms) and against the loss of endogenous substances (for example water, electrolytes and natural moisture-binding substances).
If the natural function of the skin is disturbed, increased absorption of toxic and/or allergenic foreign substances or attack by pathogenic microorganisms and, as a consequence, inflammatory or allergic skin reactions may occur.
The human skin constantly loses a certain amount of moisture by endogenous mechanisms, as it does by transpiration. However, the skin also loses important functional constituents due to external influences, such as daily washing of the body, wind and weather. Although healthy skin is entirely capable of compensating this loss, the aim of skincare is to assist the skin in compensating this loss. However, precisely when the natural regeneration capacity is inadequate, for example due to severe stress or even an illness, regulation of skin moisture and other relevant contents is essential.
The aim of skincare is thus to re-establish and promote a normal functional profile of the skin and integumentary appendages.
The following methods of skincare are known per se:
a) Occlusion of the Skin
If the skin is covered with a film of lipid or lipid/water (conventional ointments or creams), the barrier function of the skin is not re-established directly. The lipid film is an external physical protective layer.
b) Treatment of the Skin With Essential Fatty Acids
Essential fatty acids are currently occasionally employed in dermatological preparations for treatment of dry skin.
c) Treatment of the skin with substances having a keratolytic action (for example urea, salicylic acid and the like). These substances have a keratolytic, proteolytic, penetration-promoting, epidermis-thinning, antipruritic or water-binding action, depending on their nature and the concentration used. Their use is essentially limited to medical indications.
d) Treatment with moisture-regulating substances (for example glycerol, sorbitol and the like). The group of these substances is of particular interest, since it includes many representatives which have a good action. Nevertheless, a disadvantage is that most of these substances either are expensive or can be incorporated into cosmetic formulations only under complicated conditions. The statements under point c) furthermore apply to some representatives of this group.
Skincare cosmetic formulations include, in particular, cosmetic emulsions, that is to say W/O emulsions.
Emulsions of this type can on the one hand be employed without an active compound, a good action in general already being achieved, but on the other hand emulsions containing active compounds are being used more and more. It was thus an object of the present invention to provide W/O emulsions which both can function as a vehicle for active compounds of the most diverse types and also have outstanding dermatological properties without an active compound.
A disadvantage of many water-in-oil emulsions of the prior art is furthermore that they are not stable towards physical decomposition. The undesirable behaviour which occurs the most frequently is usually called "oiling out". This means that the aqueous phase and oily phase gradually separate. This manifests itself, for example, in drops of oil emerging from a W/O cream (=water-in-oil cream). However, once an emulsion has started to decompose, this process cannot be reversed again by simple means. At least, such means are not available to the user.
W/O emulsions are particularly sensitive towards a content of highly surface-active substances, the water-solubility of which is high, in contrast to
Kropke Rainer
Pape Wolfgang
Schneider Gunther
Stahl Wilhelm
Wiesner Matthias
Beiersdorf Aktiengesellschaft
Hoechst Aktiengesellschaft
Mosley Terressa
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