Process for producing stable .alpha.-L-aspartyl-L-phenylalanine

Details Process for producing stable .alpha.-L-aspartyl-L-phenylalanine Process for producing stable .alpha.-L-aspartyl-L-phenylalanine

1987-08-11

1989-05-30

Gray, Bruce D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C07C10102

Patent

active

048353019

ABSTRACT:
A process for producing stable .alpha.-L-aspartyl-L-phenylalanine methyl ester, which comprises heat-treating crystals of .alpha.-L-aspartyl-L-phenylalanine methyl ester having a water content of from 5 to 15% by weight based on wet crystals, at a temperature of higher than 50.degree. C. and lower than 80.degree. for at least 30 minutes.

REFERENCES:
patent: 4579747 (1986-09-01), Sugiyama et al.
Perry et al, Chemical Engineers' Handbook, 5th Ed., McGraw-Hill, New York, pp. 20-24 to 20-16 (1973).
"Application Potential for Aspartame in Low Calorie and Dietetic Foods", In Low Calorie and Special Dietary Foods, pp. 59-114, CRC Press 1978, CFR 21, Food and Drugs revised as of Apr. 1, 1981.

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