Pet chewable products with enzymatic coating

Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Oxidoreductases

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Details

424 941, 424 942, 424 9461, 424441, 424 943, A61K 3750

Patent

active

053364945

ABSTRACT:
An orally chewable, enzymatically coated product is provided which, upon chewing, produces an anti-bacterial and bacteriostatic effect in the oral cavity by activation of an enzymatic system contained within the coating. The enzymatic surface coating is developed, in substantially dry form, from a thickened, aqueous coating solution having a viscosity from about 1,000 to about 50,000 centipoises and containing oxidizable substrate and oxidoreductase enzymes specific to such substrate for producing hydrogen peroxide upon oral chewing of the coated product and optionally, but advantageously, further containing peroxidatic peroxidase and an alkali metal salt of an oxygen accepting anion for interacting with hydrogen peroxide to produce oxidized anionic bacterial inhibitor. An illustrative enzymatic system for this purpose contains glucose, glucose oxidase, potassium thiocyanate and lactoperoxidase. The thickened enzymatic solution suppresses the enzymatic reaction during the preparation and application of the solution to the surface of the chewable product.

REFERENCES:
patent: 4150113 (1979-04-01), Hoogendoorn
patent: 4178362 (1979-12-01), Hoogendoorn
patent: 4269822 (1981-05-01), Pellico
patent: 4537764 (1985-08-01), Pellico
patent: 4569519 (1986-01-01), Pellico
patent: 4576817 (1986-03-01), Montgomery
patent: 4578265 (1986-03-01), Pellico
patent: 4617190 (1986-10-01), Montgomery
patent: 5114704 (1992-05-01), Spanier

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