Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-12-22
1997-03-04
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514318, 546194, 546209, A61K 31445, C07D21160
Patent
active
056079524
ABSTRACT:
The invention concerns compounds of formula ##STR1## in which R, A, R.sub.1 and Y are as defined in claim 1. The instant compounds have an affinity for the fibrinogen receptor: the complex of the glycoproteins IIb/llIa (GP IIb/IIIa); more particularly, the subject of the present invention is new inhibitors of platelet aggregation which are antagonists of the GP IIb/IIIa receptors, of nonpeptide structure, which are active via the parenteral and oral routes.
REFERENCES:
patent: 5405848 (1995-04-01), Sanfillipo et al.
Badorc Alain
Bordes Marie-Fran.cedilla.oise
De Cointet Paul
Herbert Jean-Marc
Maffrand Jean-Pierre
Dahlen Garth M.
Ivy C. Warren
Sanofi
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