Pyrrolidinyl tachykinin receptor antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546187, A61K 31445, C07D40114

Patent

active

056079478

ABSTRACT:
This invention provides a novel series of substituted pyrrolidines which are useful in the treatment or prevention of a physiological disorder associated with an excess of tachykinins. This invention also provides methods for the treatment of such physiological disorders as well as pharmaceutical formulations which employ these novel compounds.

REFERENCES:
patent: 5340822 (1994-08-01), Emonds-Alt
patent: 5472978 (1995-12-01), Baker
Vaught, J L (1988) Life Sci. 43 pp. 1419-1431.

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