Method of preparation of insoluble biologically active compounds

Details Method of preparation of insoluble biologically active compounds Method of preparation of insoluble biologically active compounds

1976-03-24

1978-04-18

Tanenholtz, Alvin E.

Textiles: fiber preparation

195 63, 195DIG11, 424 12, 526312, C07G 702

Patent

active

040850056

ABSTRACT:
The invention relates to biologically active insoluble compounds on a carrier containing in its side chains a p-phenylene-diamine skeleton, where a polymer of the general formula I ##STR1## where R.sub.1 is a polymer residue, R.sub.2 is a lower alkyl group, x = 1-4, is oxidized in the presence of a soluble biologically active compound containing a primary amino group, such as e.g. enzymes, coenzymes, inhibitors of enzymes, hormones, or antigens. The oxidation is carried out by using an oxidation agent which does not disturb the biologically active compounds present in the mixture.

REFERENCES:
patent: 3706633 (1972-12-01), Katchalski et al.
patent: 3745088 (1973-07-01), Mehltretter et al.
patent: 3970521 (1976-07-01), Zaborsky et al.
Zaborsky, "Immobilized Enzymes", published by CRC Press, (1974), pp. 17, 18 and 37.

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