DNA complexes with dyes designed for energy transfer as fluoresc

Details DNA complexes with dyes designed for energy transfer as fluoresc DNA complexes with dyes designed for energy transfer as fluoresc

1997-11-07

1999-11-02

Campbell, Eggerton A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 266, C07H 2104, C07H 2102

Patent

active

059773448

ABSTRACT:
Heteromultimeric fluorophores are provided for binding to DNA, which allow for the detection of DNA in electrical separations and preparation of probes having high-fluorescent efficiencies and large Stokes shifts. In addition, by appropriate choice of fluorescent molecules, one can use a single narrow wavelength band excitation light source, while obtaining fluorescent emissions having sufficient separation to be readily discriminated.

REFERENCES:
patent: 4737454 (1988-04-01), Dattagupta et al.
patent: 5646264 (1997-07-01), Glazer et al.
patent: 5767267 (1998-06-01), Glazer et al.
Markovits (Analy. Biochem. 94:259-264), 1979.
Gawgain et al (Biochem; 17:5078-5088, 1978.

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