Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Patent
1990-12-18
1999-11-02
Smith, Lynette R. F.
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
435471, 435468, 4352523, 4351736, C12N 120, C12N 1300
Patent
active
059768800
ABSTRACT:
In a tubular pressure chamber a drop of a DNA solution with gold particles suspended therein is atomized at the opening of a cannula by a pressure impact. The fog droplets containing the gold particles and the DNA entrained by them, are pressured by the pressure impact through a restriction at the end of the pressure chamber and thereby accelerated and focused. They subsequently traverse in free flight an evacuated specimen chamber and impact in a narrowly limited target area with a predetermined pulse, cells fixed on a holder, thereby penetrating them.
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Potrykus Ingo
Sautter Christof
Waldner Heinz
Novartis Finance Corporation
Smith Lynette R. F.
Stults Larry W.
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