Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1997-04-14
1999-03-23
Killos, Paul J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
560113, C07C 702
Patent
active
058862145
ABSTRACT:
The catalytic asymmetric hydrogenation of enol esters with a vinyllic or acetylenic substituent proceeds with extremely high enantioselectivity using a Rhodium-chiral bisphosphine catalyst. This is at variance with the hydrogenation of enol esters bearing a saturated substituent, which are hydrogenated with only marginal enantioselectivity under the same conditions.
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Blake Michael J.
Eastman Chemical Company
Gwinnell Harry J.
Harding Karen A.
Killos Paul J.
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