Nucleic acid constructs for the cell cycle-regulated expression

Details Nucleic acid constructs for the cell cycle-regulated expression Nucleic acid constructs for the cell cycle-regulated expression

1997-02-13

1999-03-23

Ketter, James

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Primate cell, per se

4353201, 536 241, C12N 510, C12N 1586

Patent

active

058858334

ABSTRACT:
Nucleic acid constructs comprising an activator sequence, a promoter module, and a structural gene are disclosed. The promoter module comprises a a CHR region and a nucleic acid sequence that binds a protein of the E2F family. These constructs are used in gene therapy, such as the treatment of disorders characterized by excess cell proliferation.

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