Pharmaceutical composition containing prostadienoic acid for reg

Details Pharmaceutical composition containing prostadienoic acid for reg Pharmaceutical composition containing prostadienoic acid for reg

1977-08-11

1978-09-19

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

424314, 424317, A61K 3122, A61K 3119, A61L 904

Patent

active

041155459

ABSTRACT:
Novel alkyl diethers of prostaglandins of the formula; ##STR1## wherein R.sub.1 is hydrogen or lower alkyl; R.sub.2 and R.sub.6 are hydrogen when Y is a single bond and R.sub.2 and R.sub.6 are absent when Y is a double bond; R.sub.3 is keto, ##STR2## R'.sub.9 is hydrogen or lower alkyl; R'.sub.10 is lower alkyl; R'.sub.11 is lower alkyl; Z.sub.1 is cis or trans --CH.dbd.CH-- or --CH.sub.2 CH.sub.2 --; Z.sub.2 is trans --CH.dbd.CH-- or --CH.sub.2 CH.sub.2 --; X is a single bond or a double bond and X is a single bond when R.sub.4 and R.sub.5 are hydrogen; Y is a single bond or a double bond; n is 1 to 5, m is 0 to 4; and the non-toxic salts. The prostaglandin ethers possess valuable pharmacological properties as modifiers of smooth muscle activity, gastric secretion, blood pressure, lipolysis and the reproductive system. The compounds also induce labor and menses and they can be used for the relief of asthma and nasal congestion. The compounds are also useful as platelet anti-clumping agents and for the inhibition of peptic ulcers.

REFERENCES:
patent: 4014989 (1977-03-01), Zaffaroni

Affiliated with

Also associated with

Rating

Pharmaceutical composition containing prostadienoic acid for reg does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmaceutical composition containing prostadienoic acid for reg, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical composition containing prostadienoic acid for reg will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2120035