4'-substituted nucleosides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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514 46, 514 47, 514 48, 514 49, 514 50, 514 51, 514934, 536 2612, 536 2613, 536 2614, 536 2626, 536 2621, A61K 3170, C07H 1700, C07H 1512

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051927497

ABSTRACT:
Nucleosides compounds of Formula I: ##STR1## wherein B is a purine or a pyrimidine;

REFERENCES:
patent: 3817978 (1974-06-01), Jenkins et al.
patent: 3910885 (1975-10-01), Moffatt et al.
patent: 3928319 (1975-12-01), Jenkins et al.
"Synthesis of Certain 4'-Substituted Nucleosides", Verheyden et al., Ann. N.Y. Acad. Sci. 255, 151 (1975).
"4'-Substituted Nucleosides. 1. Synthesis of 4'-Methoxyuridine and Related Compounds", Verheyden et al., Journal of the American Chemical Society, 97(15), 4386 (1975).
"4-Substituted Nucleosides. 2. Synthesis of the Nucleoside Antibiotic Nucleocidin", Jenkins et al., Journal of the American Chemical Society, 98:11, 3346, (1975).
"Sythesis of 4'-Methoxyadenosine and Related Compounds", Verheyden et al., Carbohydrate Research, 100, 312 (1982).
"Nucleoside 4',5'-Enol Acetates. Synthesis and Chemistry of a Unique Uridine O.sup.2,4'-Anhydronucleoside", Cook et al., Journal of the American Chemical Society, 101(6), 1554 (1979).

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