Method and apparatus for deriving oxygen association rate curves

Chemistry: physical processes – Physical processes – Crystallization

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356 39, 356 41, 356205, 356246, G01N 2124, G01N 3316

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active

RE0297690

ABSTRACT:
A method and apparatus for deriving an oxygen association [rate] curve for a blood sample wherein the sample is introduced into a transparent-walled cell and is deoxygenated by contact with a deoxygenated fluorocarbon material. The cell is located in the optical path of two time-shared respective monochromatic beams, one having a wavelength at which there is substantially no change in absorbance as between oxygenated and deoxygenated blood and the other having a wavelength at which there is a relatively large change in absorbance as between oxygenated and deoxygenated blood. The difference in absorbance through the cell of the two wavelengths is measured and recorded while oxygenated fluorocarbon titrant material is pumped through the cell, the cell having a restricted flow passage for the titrant material which acts to separate the blood therefrom and retain it in the cell while the titration is taking place.

REFERENCES:
patent: 2685815 (1954-08-01), Mayne
patent: 3029682 (1962-04-01), Wood
patent: 3572995 (1971-03-01), Martin
patent: 3763422 (1973-10-01), MacPhee
patent: 3779708 (1973-12-01), Runck
patent: 3787124 (1974-01-01), Lowy
patent: 3864084 (1975-02-01), Folkman
patent: 4014649 (1977-03-01), Kiesow
Chemical Abstracts, 73, 11325t, (1970).

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