Benzoheterazolo[3,2-a]quinolinium salts

Details Benzoheterazolo[3,2-a]quinolinium salts Benzoheterazolo[3,2-a]quinolinium salts

1983-06-16

1986-05-20

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 41, C07D47104, C07D51704

Patent

active

045902755

ABSTRACT:
The preparation of the hitherto unknown benzoheterazolo[3,2-a]quinolinium salts via, the photochemically induced cyclization of 2-chlorostyrylbenzoheterazoles is described. The new products show cytotoxic, antitumor and antiviral activity.

REFERENCES:
patent: 3541100 (1970-11-01), Ramirez et al.
Fozard, et al., J. Org. Chem., vol. 31, pp. 2346-2349, (1966).
Cox, et al., J. Med. Chem., vol. 25, No. 11, pp. 1378-1381, (11/82).
Cox, et al., 9th Annual Minority Biomedical Research Support Symposium, Sponsored by the Division of Research Resources, NIH, Albuquerque, N.M., Apr. 1981, Abstr. 483.
Bubnovskaya, et al., Chemical Abstracts, vol. 69, 11405m, (1968).

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