Solubilization of protein aggregates

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.

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530355, 530417, 530418, 530419, 530422, 530423, C07K 312

Patent

active

047974745

ABSTRACT:
A method for the recovery of proteins which method includes providing a source of protein in an insoluble form, a source of at least one cationic surfactant; treating the insoluble protein with the at least one cationic surfactant in an amount sufficient to effect solubilization without substantial modification to the structural backbone of the protein.

REFERENCES:
patent: 4656255 (1987-04-01), Seely
patent: 4659568 (1987-04-01), Heilman, Jr.

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