Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1994-11-30
1996-03-12
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424451, 514909, 514910, A61K 920
Patent
active
054984246
ABSTRACT:
The present invention provides a simple, pharmacological method for treating obesity without risk of undesirable side effects. It has been discovered that intake of a megadose of a macrolide antibiotic creates an anorexigenic reaction in the human sufficient to result in weight loss. This method can also be used advantageously to assist non-obese persons in losing weight. The present invention relates to a method of treating obesity, comprising the steps of identifying a patient needing to lose weight and administering an appetite suppressing dose of a macrolide antibiotic compound to the patient. The dose of the macrolide antibiotic preferably ranges between a dose greater than a normal clinical dose used to treat bacterial infections and a maximum dose capable of being safely received by the patient without toxicity. In another preferred embodiment, the method includes the additional step of readministering the dose at an interval as required to maintain a desired level of appetite suppression throughout the treatment. In a preferred embodiment of the present invention, the macrolide antibiotic compound is clarithromycin.
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Page Thurman K.
Spear James M.
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