Optically active isoxazole derivatives

Details Optically active isoxazole derivatives Optically active isoxazole derivatives

1992-06-30

1993-11-30

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D26120

Patent

active

052667030

ABSTRACT:
The present invention relates to novel optically active isoxazole derivatives represented by general formula: ##STR1## which are useful as intermediates for synthesis of prostaglandin and a process for producing the same as well as novel aldehyde compounds represented by general formula: ##STR2## which are intermediates for preparing the compounds [XI] described above and a process for preparation thereof. In the compounds shown by these formulae, R.sup.1 represents an alkyl group or a cycloalkyl group which may have an alkoxy group or a group shown by -Ra-A-B (wherein Ra is an alkyl group; A is a hetero atom or an single bond; and B is an aromatic or hetero ring which may have a substituent(s)); and R.sup.2 and R.sup.3, which may be the same or different, each represents an aralkyl group, a silyl group or an acyl group.

REFERENCES:
patent: 4430354 (1984-02-01), Boden et al.
CA 101:23169e Intramolecular . . . PGF.sub.2.alpha.. Kozikowski et al., p. 572, 1984.
J. Org. Chem., Kozikowski et al., 49(13), 2301-9, 1984.
CA 116:128906f Optically . . . Preparation. Takahashi et al., 1992.

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