Aqueous composition comprising active ingredients for the de-pig

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

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424 62, A61K 9127, A61K 700

Patent

active

061239593

ABSTRACT:
The present invention discloses aqueous compositions comprising liposomes of phospholipids, and at least one competitive inhibitor of an enzyme for the synthesis of melanin, in combination with at least one non-competitive inhibitor of an enzyme for the synthesis of melanin. The invention also includes the use of the compositions of this invention for the de-pigmentation of skin.

REFERENCES:
patent: 5279834 (1994-01-01), Meybeck
Holdsworth (1972) Chromones in Aloe Species, Part I --Aloesin, PM 19(4):322.
Holdsworth (1972) Chromones in Aloe Species, Part II --Aloesone, PM 22(1):54.
Lee and Kim (1995) Cosmetics and Toiletries 110:51-56.
Yagi et al. (1987) Planta Medica 515.
Hirata and Suga (1977) 32c:731-734, Biologically Active Constituents of Leaves and Roots of Aloe arborescens var. natalensis.
Gombert (1997) Cosmetics and Toiletries Manufacture Worldwide, pp. 151-157.

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