Hydroxyalkylquinoline ether acids as leukotriene antagonists

Details Hydroxyalkylquinoline ether acids as leukotriene antagonists Hydroxyalkylquinoline ether acids as leukotriene antagonists

1991-10-10

1993-11-30

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142352, 514311, 514314, 544 62, 544121, 544128, 546167, 546171, 546172, 546174, A61K 3154, A61K 3147, C07D21512

Patent

active

052665682

ABSTRACT:
Compounds having the formula I: ##STR1## are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.

REFERENCES:
patent: 4920130 (1990-04-01), Haang et al.
patent: 4929626 (1990-05-01), Mohrs et al.
patent: 4962203 (1990-10-01), Young et al.

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