Method and apparatus for continuous sample ice matrix production

Radiant energy – Ionic separation or analysis – With sample supply means

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422 81, 7386311, 7386481, H01J 4904

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active

051719894

ABSTRACT:
A method and apparatus for continuously introducing samples for mass spectrometry analysis which comprises providing sample molecules in an aqueous solution containing one or more organic solvents, preferably ethylene glycol, introducing said aqueous solution into the vacuum chamber of an ion source to enable said solution to solidify into a thread of solid matrix, and exposing the solid matrix to a source of energy to desorb sample molecules to be analyzed. The desorbed molecules are then photoionized and focused into a mass spectral analysis zone. The technique is suitable for interfacing liquid chromatographic separation techniques.

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