Process of cleaving nucleic acids with oxoruthenium(IV) complexe

Details Process of cleaving nucleic acids with oxoruthenium(IV) complexe Process of cleaving nucleic acids with oxoruthenium(IV) complexe

1991-08-05

1992-12-15

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 28, 536 29, 546 2, C07H 2100

Patent

active

051718537

ABSTRACT:
A method of cleaving nucleic acids comprises contacting a nucleic acid to an oxoruthenium(IV) coordination complex. Examples of coordination compounds useful for carrying out the method include Ru.sup.IV (tpy)(bpy)O.sup.2+, Ru.sup.IV (typ)(phen)O.sup.2+, Ru.sup.IV (typ)(tmen)O.sup.2+, Ru.sup.IV (bpy).sub.2 (py)O.sup.2+, and Ru.sup.IV (phen).sub.2 (py)O.sup.2+.

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