Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-05-01
1991-02-12
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546261, 546278, 546281, 546283, 546284, 546288, C07D21357, C07D21362, C07D40112, A61K 3144
Patent
active
049924524
ABSTRACT:
Novel 5-acyl-2-(1H)-pyridinones and their use as cardiotonic agents. Typical of the compounds is 5-acetyl-1,2-dihydro-6-methyl-2-oxo-3-pyridinecarbonitrile which is prepared by condensing anionic cyano acetamide with 3-[(dimethylamino)methylenyl]-2,4-pentanedione in an inert organic solvent.
REFERENCES:
patent: 4412077 (1983-10-01), Lesher et al.
patent: 4568751 (1986-02-01), Jones et al.
patent: 4731371 (1988-03-01), Jones et al.
Dage Richard C.
Jones Winton D.
Schnettler Richard A.
Merrell Dow Pharmaceuticals Inc.
Rotman Alan L.
Sayles Michael J.
LandOfFree
Certain 5-acyl-2-(1H)-pyridinones useful in treating cardiac fai does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Certain 5-acyl-2-(1H)-pyridinones useful in treating cardiac fai, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Certain 5-acyl-2-(1H)-pyridinones useful in treating cardiac fai will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-20857