Process for effecting high efficiency separations by capillary e

Chemistry: electrical and wave energy – Processes and products – Electrostatic field or electrical discharge

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204299R, G01N 2726, B01D 5702

Patent

active

051924056

ABSTRACT:
Capillary electrophoresis is effected by introducing into a capillary a buffer solution a zwitterion composition comprised of substantially equal numbers of positive and negative charges when the negative charges are desired from sulfonate or sulfate groups and the positive charges are derived from quaternary amines, quaternary phosphines or quanternary arsines. A sample is introduced into the capillary and an electric field is established through the capillary to cause the sample to migrate through the capillary.

REFERENCES:
patent: 4675300 (1987-06-01), Zare
"Capillary Electrophoresis of Proteins in Buffers containing High Concentrations of Zwitterionic Salts", J. Chromatography, 480 (1989) 301-310, Bushey.
Swedberg, "Use of non-ionic and zwitterionic surfactants to enhance selectivity in high performance capillary Electrophoresis", J. Chromatography, 503 (1990) 449-452.

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