Method for determining minimum inhibitory concentration of antib

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195127, C12K 104

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active

039830063

ABSTRACT:
A method of determining minimum inhibitory concentration (MIC) of an antibiotic by continuously measuring the change in optical properties in response to the bacterial growth rate of a bacterial suspension in the absence and the presence of the antibiotic. The method is carried out in an automatic biological fluid analyzer.

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patent: 3772154 (1973-11-01), Isenberg et al.
patent: 3832532 (1974-08-01), Praglin et al
patent: 3895661 (1975-07-01), Praglin et al.
Heman-Ackah, "Microbial Kinetics of Drug Action Against Gram-Positive and Gram-Negative Organisms" J. Pharmaceutical Sciences 63:7 (1974) pp. 1077-1083.
Garrett et al. "Kinetics & Mechanisms of Action of Drug on Microorganisms" J. Med. Chem. vol. 12, 1969, pp. 740-745.

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