Transdermal nitroglycerin patch with penetration enhancers

Details Transdermal nitroglycerin patch with penetration enhancers Transdermal nitroglycerin patch with penetration enhancers

1992-02-04

1993-11-16

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424449, 424484, 424487, 514946, 514947, A61F 1302

Patent

active

052621650

ABSTRACT:
A transdermal nitroglycerin patch exhibiting superior nitroglycerin skin penetrating characteristics comprising a percutaneous penetration enhancer is disclosed, wherein the penetration enhancer may be one or more of N-methyl-2-pyrrolidone, oleic acid, oleyl butanediol, linoleic acid, isopropyl linoleate, azone and alcohol. Also disclosed is a transdermal patch design comprising two concentric rings, wherein the concentrations of nitroglycerin and the permeability enhancer are varied.

REFERENCES:
patent: 3711602 (1973-01-01), Herschler
patent: 4291015 (1981-09-01), Keith et al.
patent: 4305936 (1981-12-01), Klein
patent: 4322433 (1982-03-01), Leslie et al.
patent: 4409206 (1983-10-01), Sticker
patent: 4455146 (1984-06-01), Noda et al.
patent: 4537776 (1985-08-01), Cooper
patent: 4557934 (1985-12-01), Cooper
patent: 4666441 (1987-05-01), Andriola et al.
patent: 4751087 (1988-06-01), Wick
patent: 4863970 (1989-05-01), Patel et al.
patent: 4879119 (1989-11-01), Konno et al.
patent: 5023085 (1991-06-01), Francoeur
patent: 5059628 (1991-10-01), Tsuda
patent: 5079008 (1992-01-01), Sinnreich
J. Pharm. Sci, 73, No. 8 (1984) pp. 1153-1156.
J. Pharm. Sci., 64, No. 3 (1975) pp. 397-401.
Transdermal Delivery of Drugs, vol. 1, Chap. 11, A. F. Kydonieu, ed., pp. 145-156.

Affiliated with

Also associated with

Rating

Transdermal nitroglycerin patch with penetration enhancers does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Transdermal nitroglycerin patch with penetration enhancers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Transdermal nitroglycerin patch with penetration enhancers will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-20784