Process for the preparation of 4-oxoimidazolinium salts

Details Process for the preparation of 4-oxoimidazolinium salts Process for the preparation of 4-oxoimidazolinium salts

1997-02-03

1997-12-16

Ambrose, Michael G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

5483164, 5483255, C07D23332, C07D23502

Patent

active

056987048

ABSTRACT:
4-Oxoimidazolinium salts of the general formula: ##STR1## wherein R.sup.1 and R.sup.2 independently of one another are C.sub.1-10 -alkyl, C.sub.2-10 -alkenyl, C.sub.3-7 -cycloalkyl or optionally substituted aryl, arylalkyl, heteroaryl or heteroarylalkyl, or R.sup.1 and R.sup.2, together with the carbon atom to which they are bonded, form a three-membered to seven-membered saturated or unsaturated carbocyclic or heterocyclic ring, R.sup.3 is a C.sub.1-10 -alkyl group, C.sub.1-10 -alkenyl group, C.sub.3-7 -cycloalkyl group, aryl group, arylalkyl group or heteroaryl group, and A.sup.-- is an anion of a strong acid, are prepared by the cyclization of an .alpha.-acylaminonitrile in a nonaqueous solvent, in the presence of a lower alcohol and a strong acid. The compounds are intermediates for pharmaceutical active substances, for example, angiotensin II antagonists.

REFERENCES:
patent: 5424450 (1995-06-01), Boswell et al.

Affiliated with

Also associated with

Rating

Process for the preparation of 4-oxoimidazolinium salts does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of 4-oxoimidazolinium salts, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of 4-oxoimidazolinium salts will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-207775