3-[(8-Carboxy-6-tetraz olo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(

Details 3-[(8-Carboxy-6-tetraz olo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-( 3-[(8-Carboxy-6-tetraz olo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(

1980-04-08

1982-05-25

Coughlan, Jr., Paul M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544 27, 544236, A61K 31545, C07D50156

Patent

active

043316662

ABSTRACT:
Heterocyclyl derivatives of oxy-imino-substituted cephalosporins are disclosed, such, for instance the compound 3-[(8-amino-6-tetrazolo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(2-amino-4-thi azolyl)-2-methoxyimino-acetamido]-3-cephem-4-carboxylic acid and its pharmaceutically and veterinarily acceptable salts. The compounds of the application have high antibacterial activity against Gram-positive and Gram-negative bacteria, including strong beta-lactamase producer Gram-negative microorganisms.

REFERENCES:
patent: 4268509 (1981-05-01), Teraji et al.
patent: 4278793 (1981-07-01), Durckheimer et al.

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