Cyclic amides

Details Cyclic amides Cyclic amides

1998-09-22

2000-06-13

Seaman, D. Margaret

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548210, 548211, A61K 314015, A61K 31428, C07D27504

Patent

active

060750413

ABSTRACT:
Cyclic amides are inhibitors of tumor necrosis factor and can be used to combat cachexia, endotoxic shock, and retrovirus replication. A typical embodiment is 3-phenyl-3-(1-oxoisoindolin-2-yl)propionamide.

REFERENCES:
patent: 4173652 (1979-11-01), Bruins et al.
patent: 4820828 (1989-04-01), Demers et al.
Chemical Abstracts 74:53519, Joensson, 1970.
Chemical Abstracts 88:170025, Svahn, 1978.
Chemical Abstracts 65:16910h, Crook, 1969.
Chemical Abstracts 106:138317, Svoboda, 1986.
Chemical Abstracts 58:5653g, Pettit, 1967.
L.J. Denis, et al. (1997), Investigational New Drugs, vol. 15, pp. 175-185.
Slawomir M. Wojtowicz-Praga, et al. (1997), Investigational New Drugs, vol. 15, pp. 61-75.
Anita E. Yu, et al. (Sep. 11, 1997), Drugs & Aging, vol. 3, pp. 229-244.
Kuniyoshi Tanaka, et al. (Feb. 21, 1983), Chem Pharm. Bulletin, vol. 31, pp. 2810-2819.
Theodore J. Torphy (1998), Respri Crit Care Med, vol. 20, pp. 351-370.
Malcolm M. Palfreyman (1995), Drugs of the Future, vol. 20, pp. 193-804.
K. Eger, et al. (1990), Arzneim-Forsch Drugs Res., vol. 40, pp. 1073-1075.
B. Naafs, M.D., et al. (1985), International Journal of Dermatology, vol. 24, pp. 131-134.
Catherine Burnout, et al. (1998), Annual Report in Medicinal Chemistry, vol. 33, pp. 91-109.
George W. Muller, et al. (May 3, 1996), Journal of Medicinal Chemistry, vol. 39, pp. 3238-3240.
James B. Summers, et al. (1998), Annual Reports in Medicinal Chemistry, vol. 33, pp. 131-149.
Mauro M. Teixeira, et al. (May 1997), TiPS, pp. 164-170.
Laura G. Corral, et al. (Jul. 1996), Molecular Medicine, vol. 2, pp. 506-515.
Edward F. Kleinman, e al. (Oct. 9, 1997), Journal of Medicinal Chemistry, vol. 41, pp. 266-270.
Jose Maria Palacios, et al. (1995), Il Farmaco, vol. 50, pp. 819-826.
A.U. De, et al. (Aug. 9, 1974), Journal of Pharmaceutical Sciences, vol. 64, pp. 262-266.
Von E. Friderichs, et al. (1982), Arzneimittel-Forschung, vol. 32, pp. 613-620.
Claude L.. Gillet, et al (Sep. 19, 1969), Journal of Medicinal Chemistry, vol. 13, pp. 211-213.
Daniel E. Levy, et al. (Jul. 29, 1997), Journal of Medicinal Chemistry, vol. 41, pp. 199-223.
Douglas H. Steinman, et al. (Mar. 3, 1998), Bioorganic & Medicinal Chemistry, Letters, vol. 8, pp. 2087-2092.
Mark I. Crockett, et al., Biochem. Soc. Symp., vol. 63, pp. 295-313.
Michael G. Natchus, et al. (Mar. 17, 1998), Bioorganic & Medicinal Chemistry Letters, vol. 8, pp. 2077-2080.

Affiliated with

Also associated with

Rating

Cyclic amides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cyclic amides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cyclic amides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2068991