Small molecular weight ligand-hexose containing clearing agents

Details Small molecular weight ligand-hexose containing clearing agents Small molecular weight ligand-hexose containing clearing agents

1994-12-07

2000-06-13

Duffy, Patricia A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 24, 514 25, 514 54, 514 61, 514 62, A01N 4304, A61K 3170

Patent

active

060750103

ABSTRACT:
Small molecule weight clearing agents containing ligands such as biotin or biotin analogs and hexose residue, in particular galactose or N-acetyl galactosamine residues are taught. These clearing agents effectively clear anti-ligand containing conjugates in vivo via hepatocyte receptor mediated clearance mechanisms.

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