Antipsychotic 5-fluoro-pyrimidin-2-yl piperazine compound

Details Antipsychotic 5-fluoro-pyrimidin-2-yl piperazine compound Antipsychotic 5-fluoro-pyrimidin-2-yl piperazine compound

1984-03-26

1986-04-08

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544230, 544295, C07D40114, C07D40106, C07D40304, A61K 31505

Patent

active

045813574

ABSTRACT:
8-[4-[4-(5-Fluoro-pyrimidin-2-yl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decan e-7,9-dione and its pharmaceutically acceptable salts demonstrate antipsychotic activity.

REFERENCES:
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patent: 3717634 (1973-02-01), Wu et al.
patent: 3907801 (1975-09-01), Wu et al.
patent: 3976776 (1976-08-01), Wu et al.
patent: 4182763 (1980-01-01), Casten et al.
patent: 4423049 (1983-12-01), Temple, Jr.
Y. H. Wu, et al., J. Med. Chem., 15/5, 477-479 (1972).
Y. H. Wu, et al., Journal Medicinal Chemistry, 12/4, 876-881 (1969).

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