Method of conferring immunotolerance to a specific antigen

Details Method of conferring immunotolerance to a specific antigen Method of conferring immunotolerance to a specific antigen

1985-04-17

1987-07-21

Kight, John

Drug, bio-affecting and body treating compositions

Lymphokine

424 86, 424 87, 424 88, 424 89, 424 90, 424 91, 424 92, 514885, 435810, 436548, 436512, 436506, 436811, 436547, A61K 3900, A61K 3935, A61K 39395

Patent

active

046817603

ABSTRACT:
A method of selectively suppressing the immune system and conferring immunotolerance against a specific antigen by interferring with the L3T4 differentiation antigens on helper T cells is described. Simultaneous administration of a binding moiety specific for the L3T4-equivalent in the subject species and a specific antigen results in a diminished ability of the subject to respond immunologically to the antigen, whether or not the subject has been exposed previously to the antigen.

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