Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1996-07-26
1999-02-16
Killos, Paul J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
A01N 3728
Patent
active
058721525
ABSTRACT:
Various known compounds which are matrix metalloprotease inhibitors have been found to be useful in the preparation of agents for promoting tumour regression and/or inhibiting cancer cell proliferation.
REFERENCES:
patent: 5256657 (1993-10-01), Singh et al.
Liotta et al., "Cancer Metastasis and Angiogenesis: An Imbalance of Positive and Negative Regulation," Cell, 84:327-336 (1991).
Tamargo et al., "Angiogenesis Inhibitation by Minocycline," Cancer Research, 51:672-675 (1991).
Faucher, et al., "An Inhibitor of Mammalian Collagenase . . . Actinomycete Culture Broth," J. Antibiotics, vol. XI, No. 12, pp. 1757-1761 (1987).
Bawden Lindsay Jayne
Brown Peter Duncan
Miller Karen Margrete
British Biotech Pharmaceuticals Limited
Killos Paul J.
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