Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-01-27
1999-02-16
Zitomer, Stephanie W.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 911, 435 912, 435 9151, 536 221, C12Q 168, C12P 1934, C07H 2104
Patent
active
058719245
ABSTRACT:
The instant invention provides a method for identifying and preparing nucleic acid ligands capable of facilitating aminoacyl-RNA synthesis. The nucleic acid ligands are identified and produced by exposure of candidate nucleic sequences to a reactant under conditions conducive to reaction, wherein nucleic acid sequences having facilitative activity are able to facilitate or enhance a reaction between the reactant molecule and nucleic acid sequence. Included in the invention are specific RNA ligands capable of facilitating aminoacyl-RNA synthesis identified by the SELEX method.
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Illangasekare Mali
Yarus Michael
NeXstar Pharmaceuticals, Inc.
Tung Joyce
Zitomer Stephanie W.
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