Process for the production of acylated 1,3-dicarbonyl compounds

Details Process for the production of acylated 1,3-dicarbonyl compounds Process for the production of acylated 1,3-dicarbonyl compounds

1986-06-09

1987-09-22

Reamer, James H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568341, 568346, 568384, 568388, 568314, C07C 4554

Patent

active

046956735

ABSTRACT:
An acylated 1,3-dicarbonyl compound is produced by rearrangement of the corresponding enol ester in the presence of a cyanide source. In one embodiment the cyanide source is employed with a molar excess of a moderate base, with respect to the enol ester. In another embodiment, the cyanide source is a stoichiometric amount, with respect to the enol ester, of potassium or lithium cyanide and a catalytic amount of a crown ether is used.

REFERENCES:
patent: 3153612 (1974-10-01), Molko et al.
patent: 4448965 (1985-05-01), Henrick
patent: 4482727 (1985-11-01), Lee
patent: 4545806 (1985-10-01), John et al.
patent: 4555263 (1985-11-01), Seiban et al.
patent: 4560403 (1985-12-01), Motojima et al.
patent: 4584013 (1986-04-01), Brunner
Akhram et al., Synthesis, pp. 925-927 (1978).
Tanabe et al., Chem. Letters, p. 53 (1952).
Shiori et al., J. Org. Chem., vol. 43, pp. 3631-3632 (1978).
Nogia et al., J. Chem. Soc., Chem. Comm., pp. 459-6 (1985).
Koto et al., Chem. Pharm. Bull., pp. 1679-1682 & 3323-3326 (1984).

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