Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1996-09-27
1998-04-21
Tsang, Cecilia J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 16, 514 17, 514 18, 530317, 530322, 530328, 530329, 530330, A61K 3800, C07K 500, C07K 700, C07K 1700
Patent
active
057417741
ABSTRACT:
The present invention relates to the use of a cytokine regulatory agent to reduce the severity of rheumatoid arthritis.
REFERENCES:
patent: 5420109 (1995-05-01), Suto et al.
patent: 5457129 (1995-10-01), Aggarwal et al.
Arai et al. Cytokines:Coordinators of immune and inflammatory responses. Annu. Rev. Biochem. 59: 783-836 Jun. 1990.
Wooley et al., "Influence of a Recombinant Human Soluble Tumor Necrosis Factor Receptor FC Fusion Protein on Type II Collagen-Induced Arthritis in Mice," J. Immunol. 151:6602-6607 (1993).
Wooley et al., "The Effect of an Interleukin-1 Receptor Antagonist Protein on Type II Collagen-induced Arthritis and Antigen-induced Arthritis in Mice," Arthr. Rheum. 36:1305-1314 (1993).
Girten Beverly E.
Tuttle Ronald R.
Bolin Michael
Trega Biosciences, Inc.
Tsang Cecilia J.
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