Tricyclic diazepine vasopressin antagonists and oxytocin antagon

Details Tricyclic diazepine vasopressin antagonists and oxytocin antagon Tricyclic diazepine vasopressin antagonists and oxytocin antagon

1998-12-08

1999-10-19

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514 80, 5142332, 544115, 544337, 544344, 544346, A61K 31495, A61K 31535, C07D24136, C07D26530

Patent

active

059689374

ABSTRACT:
Tricyclic diazepines of the formula: ##STR1## wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.

REFERENCES:
patent: 5843944 (1998-12-01), Albright, et al.
Yamamura et al., Science , 252, pp. 572-574 (1991).
Yamamura et al., Br. J. Pharmacol., 105, pp. 787-791 (1992).

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