Keratinocyte culture from precursor cells

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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Details

435384, 5147723, 514774, A61L 1516, C12N 502, A61K 4730

Patent

active

059685468

ABSTRACT:
The present invention relates to the treatment of skin defect by organotypically cultured autologous keratinocytes isolated from the outer root sheath of hair follicles. Methods for primary as well as subsequent organotypic cultures (epidermal equivalents) in fully defined media eventually supplemented by autologous human serum and substances isolated from blood components, with minimal allogeneic biological supplements, are disclosed. Techniques to prepare epidermal equivalents for transplantation are included, as well as a method for the transport of the epidermal equivalents.

REFERENCES:
patent: 5580781 (1996-12-01), Naughton et al.

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