4-aroylpiperidine derivatives-CCR-3 receptor antagonists

Details 4-aroylpiperidine derivatives-CCR-3 receptor antagonists 4-aroylpiperidine derivatives-CCR-3 receptor antagonists

1999-11-17

2000-10-31

Seaman, D. Margaret

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514314, 514318, 546159, 546192, 546193, C07D21538, C07D21168, A61K 31445, A61K 3147, L07D21108

Patent

active

06140344&

ABSTRACT:
This invention relates to certain piperidine quaternary salts of Formula (I) ##STR1## that are CCR-3 receptor antagonists, pharmaceutical compositions containing them, methods for their use and methods for preparing these compounds.

REFERENCES:
patent: 4559349 (1985-12-01), Storni
patent: 5143923 (1992-09-01), Hrib et al.
patent: 5317020 (1994-05-01), Emonds-Alt et al.
patent: 5541201 (1996-07-01), Carr et al.
patent: 5728835 (1998-03-01), Aoki
U.S. patent application SN 09/134,013, Filing date Aug. 14, 1998, Cyclic Amine Derivatives CCR-3 Receptor Antagonists, Gong, et al. (Assignee Syntex (U.S.A.) Inc); Docket No. R0029B-REG.

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