Process for 11a-dehalogenation of 11a-halotetracyclines

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260654D, C07C10322

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041266390

ABSTRACT:
The 11a-dehalogenation of 11a-halo-6-methylenetetracyclines by treating them with a secondary or a tertiary phosphine or a tertiary phosphite.

REFERENCES:
patent: 2742510 (1956-04-01), Davis
patent: 3250809 (1966-05-01), Blackwood et al.
patent: 3413365 (1968-11-01), Sennewald et al.
patent: 3649700 (1972-03-01), Baader et al.
Borowitz et al., JACS 94:19, Sep. 20, 1972, pp. 6817-6822.

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