Chemical synthesis of 6-O-alkyl erythromycin A

Details Chemical synthesis of 6-O-alkyl erythromycin A Chemical synthesis of 6-O-alkyl erythromycin A

1997-11-17

1998-12-22

Peselev, Elli

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 185, 536 186, C07H 100, C07H 1708

Patent

active

058521801

ABSTRACT:
A process of preparing 6-O-alkyl erythromycin A is provided. The process includes the steps of protecting the oxime hydroxyl of 9-oxime erythromycin A with a benzoyl protecting group, protecting the 2'-hydroxyl group and optionally the 4'-hydroxyl group with an O-protecting group, alkylating the 6-hydroxyl, removing the benzoyl and O-protecting groups and deoximating the 9-oxime.

REFERENCES:
patent: 4331803 (1982-05-01), Watanabe et al.
patent: 4668776 (1987-05-01), Yamada et al.
patent: 4670549 (1987-06-01), Morimoto et al.
patent: 4672109 (1987-06-01), Watanabe et al.
patent: 4680386 (1987-07-01), Morimoto et al.
patent: 4990602 (1991-02-01), Morimoto et al.
patent: 5274085 (1993-12-01), Amano et al.

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