Process for separating para-cresol from a mixture of methylated

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

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C07C 3768

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042673895

ABSTRACT:
Para-cresol is separated from a mixture comprising meta-cresol and various other methylated and ethylated phenols by preferentially complexing the para-cresol with one or more anhydrous or dehydrated inorganic salts selected from the group consisting of calcium bromide, lithium bromide, manganese bromide and magnesium chloride. The anhydrous inorganic salt is added to the phenolic mixture in an amount to give a mole ratio of salt to para-cresol in the mixture in the range of about 0.5 mole to one to about 1.5 mole to one. The para-cresol and salt form a complex and the complex is removed from the mixture of methylated and ethylated phenols. Then the complex is decomposed to recover the para-cresol and salt; the recovered salt may be recycled to complex with more para-cresol.

REFERENCES:
patent: 1980384 (1934-11-01), Comte
patent: 2042331 (1936-05-01), Carswell
patent: 2366538 (1945-01-01), Luten et al.
patent: 2835714 (1958-05-01), Nixon et al.
Sharpless, et al., "Jour. Organic Chemistry", vol. 40, No. 9 (1975), pp. 1252-1257.

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