N-aminoalkyl-substituted nitrogen-containing six membered hetero

Details N-aminoalkyl-substituted nitrogen-containing six membered hetero N-aminoalkyl-substituted nitrogen-containing six membered hetero

1996-10-04

1998-12-22

Grumbling, Matthew V.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142275, 5142378, 514252, 514255, 544 582, 544111, 544121, 544130, 544160, 544359, 544383, C07D26530, C07D27912, A61K 3154, A61K 31535

Patent

active

058520066

ABSTRACT:
Disclosed are new alkylenediamine derivatives of the following formula which are effective for treatment of dysuria are disclosed: ##STR1## wherein R.sup.1 is hydrogen, alkyl, or a substituted or unsubstituted phenyl, naphthyl or aromatic heterocyclic group; R.sup.2 is a substituted or unsubstituted phenyl, naphthyl or aromatic heterocyclic group; R.sup.3 and R.sup.4 represent hydrogen, alkyl, aralkyl or aryl; or R.sup.3 and R.sup.4 are combined to form one of substituted or unsubstituted 5- to 7-membered heterocyclic groups; X is oxygen, sulfur or imino; Y is oxygen or sulfur; Z is --CH.sub.2 --, --CO-- or --CS--; m is an integer of 0-4; n is an integer of 0-4; r is 0 or 1; and p and q represent an integer of 0-5 provided that p plus q is 1-5.

REFERENCES:
Moehrle et al, Arch. Pharm. (Weinheim, Ger.) (1973) 306 (5) 325-338.

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