Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1980-01-31
1981-05-12
Trousof, Natalie
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
2602391, 544321, A61K 31505, C07D49968
Patent
active
042671809
ABSTRACT:
Novel organic amide compounds which are N-[2-[(acylaminoacylamino or aminoacylamino)phenyl]-4-hydroxy-5-pyrimidinylcarbonyl] penicillin compounds having broad spectrum antibacterial utility are provided by (a) reacting the free amino acid of the appropriate penicillin or the acid salt or silylated derivative or complex thereof with a reactive derivative of the corresponding N-2-[(acylaminoacylamino or aminoacylamino)phenyl]-4-hydroxy-5-pyrimidine carboxylic acid or (b) reacting the free amino acid of 6-aminopenicillamic acid or a related compound or the acid salt or silylated derivative thereof with a reactive derivative of the corresponding D-N-[2-[(acylaminoacylamino or aminoacylamino)phenyl]-4-hydroxy-5-pyrimidinylcarbonyl]-2-substituted glycine. Pharmaceutical compositions containing said compounds and methods for treating infections using said compositions are also disclosed.
REFERENCES:
patent: 3660403 (1972-05-01), Shen et al.
patent: 3951982 (1976-04-01), Goel
patent: 3954734 (1976-05-01), Doub et al.
patent: 4008220 (1977-02-01), Tobiki et al.
patent: 4041161 (1977-08-01), Kocisis et al.
patent: 4081441 (1978-03-01), Baker et al.
patent: 4156724 (1979-05-01), Yamada et al.
Haskell Theodore H.
Hutt, Jr. Marland P.
Nicolaides Ernest D.
Clarke Vera C.
Raines Stephen
Trousof Natalie
Warner-Lambert & Company
LandOfFree
Novel antibacterial amide compounds and process means for produc does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel antibacterial amide compounds and process means for produc, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel antibacterial amide compounds and process means for produc will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2046501